Tanduay Distillers is a Filipino rum producer owned by local business magnate Lucio Tan. The Tanduay brand originates from the Bulacan distillery in Hagonoy, originally owned by Elías Menchatorre. In 1856, the distillery was acquired by Valentín Teus e Yrisarry and transferred to Ynchausti y Compañía, a Filipino enterprise managed by the Ynchausti family. Although the Hagonoy distillery was already operational at the time of acquisition, Ynchausti y Compañía decided to use its own founding date (1854) as the distillery's founding date – meaning we're talking about over 150 years of history. Six years later, on Isla de Tanduay in Manila, a rectification plant was built which became Tanduay's target distillery.

There are no records of product names manufactured in the early days of operation, so it can generally be assumed that all alcoholic products from this period were sold without brand names and were designated only by generic names: "aguardiente" (Spanish for firewater), "tubâ" (palm wine) and "ron" (Spanish for rum). But the earliest mentions of the distillery list rum simply as "ron de destillería de Hagonoy y Tanduay" (literally "rum from the Hagonoy and Tanduay distillery"). It wasn't until the 1930s that the local rum was officially named Tanduay Rhum, and its packaging was changed from the previously used nearly 40-litre glass demijohn to the standard bottle capacities we know today.

The brand's most recent history began on 18 May 1988, when it was purchased by Twin Ace Holdings Corporation, a company owned by Lucio Tan. The new management began a programme of modernisation and expansion of the facility, resulting in the distillery's production capacity increasing almost 50-fold. On 30 July 1999, Twin Ace Holdings changed the company's name to Tanduay Distillers, Inc.

The original Tanduay distillery was the main production facility for Tanduay rum until its closure in April 2013, when production was moved to a larger facility, while part of the original distillery will be converted into a museum showcasing the brand's history and heritage.

Since 2021, Tanduay has been the world's largest rum brand (measured by litres sold).